教師基本信息
職稱：教授
電子郵箱：huiru_tang（at）fudan.edu.cn (at means @)
辦公地點：複旦生科院D105室
辦公電話：021-31246725
個人簡介
國家傑出青年科學基金獲得者、英國皇家化學會會士、狗万外围充值 特聘教授、國家重點研發計劃項目首席。1986年獲西北輕工業學院（現陝西科技大學）學士、1994年獲倫敦大學博士學位。1992-2005年先後在英國BBSRC食品研究所、帝國理工學院生物醫學部任Senior Scientist等職。2005-14年先後任中科院武漢物數所研究員、博導、研究部副主任、中科院生物磁共振分析重點實驗室創建主任。2014年加盟万博英超狼队网官方网 。曾任英國NHS、科技部973及蛋白質重大計劃等評審專家、J Proteome Res編委。在Nature及PNAS等上發表SCI論文210餘篇，被引1.2萬餘次（h指數~63）。獲批發明專利6項。部分工作被Science、Nature等作為“研究亮點”專文評述。現任國際實驗核磁共振大會（ENC）執委、中國生物物理學會代謝組學分會會長、自由基生物學及醫學分會常務理事、生物磁共振專委會委員，中國抗癌協會腫瘤代謝專委會常務理事，中國營養學會基礎營養學分會理事，Metabolomics、Curr Metabolomics、Arch Pharm和《基礎醫學與臨床》等編委，Nutrition & Metabolism及Phenomics等副主編。
Personal website: http://www.metabolome.cn/
研究方向
聚焦代謝物結構功能及代謝組學30餘年，發展高通量超靈敏代謝組學、代謝組與轉錄組/蛋白質組/微生物組數據整合分析等技術，研究重大疾病發生發展及有效幹預的分子基礎。曾主持國家傑出青年科學基金、國家重點研發計劃、國家自然科學基金重大、973課題等項目多項。現承擔國家重點研發計劃、國家創新群體、上海市級重大專項等任務。
榮譽及獲獎情況（Awards）
英國皇家化學會會士（2005）、國家傑出青年科學基金（2008）、新世紀百千萬人才工程國家級人選稱號（2009）、王天眷波譜學獎（2010）、武漢市優秀科技工作者（2011）。
1. Y. B. Feng, et al, “Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota”, Nat Microbiol, 7:707-715, 2022.【IF~31】
2. Z. M. Hou, et al, “Inhibiting 3bHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer”, Cell Rep Med, 3:100561, 2022.【IF~17】
3. J. H. Liu, et al, “Simultaneous quantification of 70 elements in biofluids within 5 min using inductively coupled plasma mass spectrometry to reveal elementomic phenotypes of healthy Chinese adults”, Talanta, 238:123720, 2022.【IF~6.6】
4. Q. Y. Hu, et al, “Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry”, Talanta, 238:123059, 2022.【IF~6.6】
5. M. F. Xia, et al, “NAFLD-related gene polymorphisms and all-cause and cause-specific mortality in an Asian population: the Shanghai Changfeng Study”, Aliment Pharm Ther, 55:705-21, 2022【IF~9.5】
6. M. F. Xia, et al, “Insights into contribution of genetic variants towards the susceptibility of MAFLD revealed by the NMR_based lipoprotein profiling”, J Hepatol, 74:974-977, 2021.【IF~30】
7. Y. Xu, et al, “Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues”, EMBO J, e108069, 2021.【IF~14】
8. M. Wang, et al, “Glucose-mediated proliferation of a gut commensal bacterium promotes Plasmodiuminfection by increasing mosquito midgut pH”, Cell Rep, 35:108992, 2021【IF~10】
9. R. Loo, et al, “A feasibility study of metabolic phenotyping of dried blood spot specimens in rural Chinese women exposed to household air pollution”, J Expo Sci Env Epid, 31:328, 2021【IF~6.4】
10. Y. P. An, et al, “Development and validation of an improved probabilistic quotient normalization method for LC/MS- and NMR-based metabonomic analysis”, Chin Chem Lett, 31:1827, 2020.【IF~8.5】
11. J. Xue, et al, “A vitamin-C-derived DNA modification catalysed by an algal TET homologue”, Nature, 569:581–585, 2019【IF~69】
12. H. Lin, et al, “Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat model”, JAFC, 67:3624. 2019.【IF~5.9; 高被引, 年均20餘次】
13. J. Gou, et al, “Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis”, Plant J, 93:92-106, 2018.【IF~7.1】
14. F. Chen, et al, “Combined metabonomic and quantitative RT-PCR analyses revealed metabolic reprogramming associated with Fusarium graminearum resistance in transgenic Arabidopsis thaliana”, Front Plant Sci, 8:2177, 2018.【IF~6.6】
15. L. Zhang, et al, “Metabolomics reveals that dietary ferulic acid and quercetin modulate metabolic homeostasis in rats”, J Agric Food Chem, 66: 1723−1731, 2018. 【IF~5.9】
16. C. Liu, et al, Dynamic metabolic responses of brown planthoppers towards susceptible and resistant rice plants, Plant Biotechnol J, 15:1346, 2017.【IF~13】
17. Q. Wan, et al, Quantitative 13C traces of glucose fate in hepatitis B virus infected hepatocytes, Anal Chem, 89:3293–3299, 2017【IF~8】
18. H. Li, et al, Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer, Cell Discov, 2:16031, 2016.【IF~38】
19. L. Sun, et al, cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions, Cell Res, 25:429, 2015.【IF~46】
20. M. Li, et al, “Human symbiotic gut microbes specifically modulate metabolic phenotypes”, PNAS, 105:2117-2122, 2008.【IF~12.8; 高被引, 年均被引>50次】
論文及引用Full Publication List [>5 citations per annum for 79 papers]
https://publons.com/researcher/2776607/huiru-tang/