教師基本信息
姓名:餘垚
職稱:副研究員
電子郵箱:yaoyu@fudan.edu.cn
辦公地點:生科院E501-2
辦公電話:021-31246578
研究方向
酵母分子遺傳學,遺傳工程,合成生物學
個人簡介
2000年,獲狗万外围充值 微生物學學士學位,2006年,獲狗万外围充值 遺傳學博士學位。2006-2011年在美國紐約州立大學石溪分校從事博士後研究。2011年7月任万博英超狼队网官方网 副研究員。目前承擔國家自然基金委麵上項目。曾獲第二屆上海高校青年教師教學競賽(自然科學基礎學科)一等獎, 被評為上海市教學能手。
授課情況
改變生命的生物技術(全國一流本科課程)
遺傳工程原理與應用
招生專業
遺傳學
代表性論文和論著
1. Yu Y†, Mo W†, Ren H, Yang X, Lu W, Luo T, Zeng J, Zhou J, Qi J*, Lu H*. 2021. Comparative genomic and transcriptomic analysis reveals specific features of gene regulation in Kluyveromyces marxianus. Front Microbiol. doi: 10.3389/fmicb.2021.598060
2.Wu L, Wang M, Zha G, Zhou J, Yu Y#, Lu H#. 2020. Improving the expression of a heterologous protein by genome shuffling in Kluyveromyces marxianus. J Biotechnol 320:11-16.
3.Zhou J†, Zhu P†, Hu X, Lu H, Yu Y*. 2018. Improved secretory expression of lignocellulolytic enzymes in Kluyveromyces marxianus by promoter and signal sequence engineering. Biotechnol Biofuels 11:235.
5.Chen Y, Hu X, Guo C, Yu Y#, Lu H#. 2017. Epe1 contributes to activation of AMPK by promoting phosphorylation of AMPK alpha subunit, Ssp2. Sci Rep 7:3208.
6.Yu Y†, Zhou H†, Deng X, Wang W, Lu H. 2016. Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast. Sci Rep 6:31752.
8.Zhou H, Liu Q, Shi T, Yu Y*, Lu H. 2015. Genome-wide screen of fission yeast mutants for sensitivity to 6-azauracil, an inhibitor of transcriptional elongation. Yeast 32:643-55.
11.Deng X, Zhou H, Zhang G, Wang W, Mao L, Zhou X, Yu Y#, Lu H#. 2015. Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast. Sci Rep 5:14707.
12.Lei B†, Zhou N†, Guo Y, Zhao W, Tan YW, Yu Y#, Lu H#. 2014. Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex. J Cell Sci 127:4024-36.
14.Pan X, Lei B, Zhou N, Feng B, Yao W, Zhao X, Yu Y#, Lu H#. 2012. Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library. BMC Genomics 13:662.
15.Yu Y, Srinivasan M, Nakanishi S, Leatherwood J, Shilatifard A, Sternglanz R*. 2011. A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast. Mol Cell Biol 31:2311-25.
17.Li Y†, Yu Y†, Zhang Y†, Zhou Y, Li C, Zhu J, Yuan H, Lu H*. 2011. MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway. Cancer Sci 102:2043-50.
18.Yu Y, Neiman AM, Sternglanz R*. 2010. The JmjC domain of Gis1 is dispensable for transcriptional activation. FEMS Yeast Res 10:793-801.
19.Kumar PR, Yu Y, Sternglanz R, Johnston SA, Joshua-Tor L*. 2008. NADP regulates the yeast GAL induction system. Science 319:1090-2.